HCID 15341788, compound → HCID 15341792, compound

HRID 1033622Notes

Reaction equation

HRID 1033622 reaction equation
[OH:1][C:2]1[C:11]([CH2:12][CH:13]=[CH2:14])=[C:10]([OH:15])[CH:9]=[CH:8][C:3]=1[C:4]([NH:6][CH3:7])=[O:5]>C(O)C.[Pd]>[OH:1][C:2]1[C:11]([CH2:12][CH2:13][CH3:14])=[C:10]([OH:15])[CH:9]=[CH:8][C:3]=1[C:4]([NH:6][CH3:7])=[O:5]

Participants

4

Reactant 1

HCID 15341788HCID 15341788, compound

Product 1

HCID 15341792HCID 15341792, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The compound of Example 6 (1.0 g) was dissolved in 30 ml of ethanol and hydrogenated at room temperature and 5 psi for 2 hours and 25 minutes using 200 mg of 4% Pd/C as catalyst. The solvent was removed under vacuum to give the product as a white solid.

Workup

  1. custom25 minutes
  2. customThe solvent was removed under vacuum

Sources & evidence

ORD record
ord-98499336c73e431a98c1450865cbc249
Source dataset
uspto-grants-1994_05
Patent number
US05310951

Reaction notes

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