Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Methyl 2,4-dihydroxy-3-(prop-2-en-1-yl)benzoate | HCID 13019279 | — |
| Solvent | Pyrrolidine | HCID 31268 | — |
| Product | HCID 15341804 | HCID 15341804 | — |
Reaction Steps
Methyl 2,4-dihydroxy-3-(2-propenyl)benzoate (3.0 g) and a few crystals of ammonium chloride were added to 20 ml of pyrrolidine. The reaction mixture was heated to 50° C. and stirred overnight. The reaction mixture was neutralized with 10% hydrochloric acid and extracted with ethyl acetate. Concentration under vacuum to remove solvent gave the product as a light brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05310951 |
|---|
| Source dataset | uspto-grants-1994_05 |
|---|
| ORD ID | ord-bfaf6736ee4e4b81a76c9616f1464f45 |
|---|
| Source note | uspto-grants-1994_05 |
|---|
