Ethyl acetate hexane → HCID 19026443, compound

HRID 1033661Notes

Reaction equation

HRID 1033661 reaction equation
[NH2:1][C:2]([C:4]1[CH:30]=[CH:29][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[C:14]([CH2:26][CH2:27][CH3:28])=[C:15]([CH:23]=[CH:24][CH:25]=2)[O:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])=[C:6]([CH2:31][CH:32]2[CH2:34][CH2:33]2)[C:5]=1[OH:35])=[O:3].[C:36](OCC)(=O)C.CCCCCC>>[CH2:21]([O:20][C:18](=[O:19])[CH2:17][O:16][C:15]1[CH:23]=[CH:24][CH:25]=[C:13]([O:12][CH2:11][CH2:10][CH2:9][O:8][C:7]2[CH:29]=[CH:30][C:4]([C:2]([NH2:1])=[O:3])=[C:5]([O:35][CH3:36])[C:6]=2[CH2:31][CH:32]2[CH2:33][CH2:34]2)[C:14]=1[CH2:26][CH2:27][CH3:28])[CH3:22]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 54373268HCID 54373268, compound

Product 1

HCID 19026443HCID 19026443, compound

Procedure

The compound of Example 70 is exposed to the conditions described in Example 25. Chromatography of the crude product on silica gel using ethyl acetate/hexane, (3:7) as eluant affords the product.

Workup

  1. customaffords the product

Sources & evidence

ORD record
ord-9a344a151ea042b4ac6cc999093ab276
Source dataset
uspto-grants-1994_05
Patent number
US05310951

Reaction notes

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