HCID 22399584, compound → HCID 21479718, compound

HRID 1033664Notes

Reaction equation

HRID 1033664 reaction equation
[NH2:1][C:2]([C:4]1[CH:33]=[CH:32][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:28]=[CH:27][C:16]3[CH2:17][CH2:18][CH:19]([CH2:21][CH2:22][C:23]([O:25]C)=[O:24])[O:20][C:15]=3[C:14]=2[CH2:29][CH2:30][CH3:31])=[C:6]([CH2:34][CH:35]2[CH2:37][CH2:36]2)[C:5]=1[O:38][CH3:39])=[O:3]>C(OCC)(=O)C.CO.C(O)(=O)C>[NH2:1][C:2]([C:4]1[CH:33]=[CH:32][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:28]=[CH:27][C:16]3[CH2:17][CH2:18][CH:19]([CH2:21][CH2:22][C:23]([OH:25])=[O:24])[O:20][C:15]=3[C:14]=2[CH2:29][CH2:30][CH3:31])=[C:6]([CH2:34][CH:35]2[CH2:37][CH2:36]2)[C:5]=1[O:38][CH3:39])=[O:3]

Participants

3

Reactant 1

HCID 22399584HCID 22399584, compound

Product 1

HCID 21479718HCID 21479718, compound

Reagents, catalysts & solvents 1

HCID 22023684HCID 22023684, compoundSolvent

Procedure

The compound of Example 74 is saponified as described in Example 62. Chromatography on silica gel with ethyl acetate/methanol/acetic acid (95:4.5:0.5) as eluant gives the product.

Sources & evidence

ORD record
ord-f2fb233c67d34ae1a6c1b2670315a808
Source dataset
uspto-grants-1994_05
Patent number
US05310951

Reaction notes

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