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HRID1033703

反应详情

EQUATION

反应方程式

HRID 1033703 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(-c2ccccc2)cc1F
HCID14122124

3-Fluoro-4-methoxy-1,1'-biphenyl

C13H11FO

结构：CC(=O)Cl.[Al+3].[Cl-].[Cl-].[Cl-]
HCID86587523

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(-c2ccc(C(C)=O)cc2)cc1F
HCID14388648

1-(3′-Fluoro-4′-methoxy[1,1′-biphenyl]-4-yl)ethanone

C15H13FO2

收率 82%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：S=C=S
溶剂HCID6348

Carbon disulfide

CS2

PROCEDURE

实验过程

3-Fluoro-4-methoxybiphenyl was acetylated with acetyl chloride/AlCl3 in carbon disulfide in the usual way. The product was twice recrystallized from toluene to obtain 3'-fluoro-4'-methoxy-4-acetylbiphenyl (yield: 82%), m.p. 149°~149.5° C.

WORKUP

后处理

  1. customThe product was twice recrystallized from toluene