Pyridine → HCID 15220889, compound

Participants

Reaction Steps

3,5-Dimethoxycarbonylbenzenesulfonyl chloride (1.9 grams) and 2 ml of pyridine were added to 2.7 grams of 5-amino-2-(3,5-disulfophenylcarbamoyl)-1-naphthol and 27 ml of N,N-dimethylacetamide. The mixture was stirred for 1 hour at room temperature and then 50 ml of ethyl alcohol were added, and the crystals which precipitated out were recovered by filtration. 30 ml of methyl alcohol, 2 grams of sodium hydroxide and 10 ml of water were added to the crystals and, after boiling under reflux for 1 hour, 5 grams of 5-(3,5-dicarboxyphenylsulfonamido)-2-(3,5-disulfophenylcarbamoyl)-1-naphthol were obtained.

Provenance & Evidence