HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → 1,2,3,4-Tetrahydroquinoline-1-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| Product | 1,2,3,4-Tetrahydroquinoline-1-carbonyl chloride | HCID 13591069 | 90% |
Reaction Steps
By the procedure of Example 7, Step A, 1,2,3,4-tetrahydroquinoline was reacted with phosgene to give a 90% yield of the title compound as a dark orange oil, homogeneous by TLC (3:1 hexane-EtOAc) but Rf identical to that of starting material; IR spectrum νCO 1740 cm-1 ; FAB-MS m/e 196 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05312820 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-e9f51f8f648a430da2349861bdac7755 |
| Source note | uspto-grants-1994_05 |