HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibenzylamine → Epinastine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibenzylamine | HCID 7656 | — |
| Reactant | N-Methylbenzylamine | HCID 7669 | — |
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Diethanolamine | HCID 8113 | — |
| Reactant | Dibutylamine | HCID 8148 | — |
| Reactant | N-Ethylbenzylamine | HCID 84352 | — |
| Product | Epinastine | HCID 3241 | — |
Reaction Steps
adding a base selected from the group consisting of N,N-dibenzylamine, N,N-dibutylamine, diethanolamine, diisopropylamine, N-ethylbenzylamine, sarcosin-Na salt and N-methylbenzylamine to the reaction mixture, to produce 3-amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05312916 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-703908ef9cd5479bbd9ec3e739d18c79 |
| Source note | uspto-grants-1994_05 |