Diethyl Ether → Lithium, 1H-inden-1-yl-

HRID 1033869Notes

Reaction equation

HRID 1033869 reaction equation
C(OCC)C.[CH2:6]([Li:10])[CH2:7][CH2:8][CH3:9].[CH3:11][CH2:12][CH2:13][CH2:14][CH2:15]C>>[CH-:6]1[C:15]2[C:9](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:8]=[CH:7]1.[Li+:10]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 8058HexaneHCID 178418339Butyllithium

Product 1

HCID 11116044Lithium, 1H-inden-1-yl-

Procedure

A 100 mL Schlenk flask is charged with diethyl ether, 50 mL, and n-butyllithium, 5.2 mL (13.88 mmole) of a 2.68M solution in hexane) at -78° C. To the magnetically stirred, chilled solution is added nitrogen degassed indene, 1.8 mL (15.27 mmole). The mixture is stirred and warmed to room temperature over 1 to 2 hours. The mixture is stirred at least an additional 4 hours at room temperature to insure complete reaction prior to further use.

Workup

  1. temperaturechilled solution
  2. additionis added nitrogen
  3. customdegassed indene, 1.8 mL (15.27 mmole)
  4. stirringThe mixture is stirred
  5. stirringThe mixture is stirred at least an additional 4 hours at room temperature
  6. customreaction

Sources & evidence

ORD record
ord-28c1681451b14d6991e9fad9487ca9e8
Source dataset
uspto-grants-1994_05
Patent number
US05312938

Reaction notes

Loading…