Boron tribromide → HCID 15144939, compound

HRID 1033905Notes

Reaction equation

HRID 1033905 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:33])[C:7](/[CH:10]=[C:11](\[CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22]C)=[C:18]([O:24]C)[CH:17]=2)/[C:12]([OH:14])=[O:13])=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4].B(Br)(Br)Br>C(Cl)Cl>[CH2:1]([C:5]1[N:6]([CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:33])[C:7](/[CH:10]=[C:11](\[CH2:15][C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[C:18]([OH:24])[CH:17]=2)/[C:12]([OH:14])=[O:13])=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 15144935HCID 15144935, compound

Product 1

HCID 15144939HCID 15144939, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

(E)-3-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(3,4-dimethoxyphenyl)methyl-2-propenoic acid, prepared in Example 28, was treated with boron tribromide in methylene chloride to give the title compound; mp 129-I33° C.

Sources & evidence

ORD record
ord-5b0dd366f06e4419ab903eef8753b8b3
Source dataset
uspto-grants-1994_05
Patent number
US05312828

Reaction notes

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