Sodium Cyanide → HCID 21261854, compound

HRID 1034021Notes

Reaction equation

[CH2:1]([O:3][C:4]1[CH:11]=[C:10]([CH2:12][C:13]([NH:15][CH:16]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)[CH2:17][CH:18]([CH3:20])[CH3:19])=[O:14])[CH:9]=[CH:8][C:5]=1[CH2:6]Cl)[CH3:2].[C-:33]#[N:34].[Na+]>>[CH2:1]([O:3][C:4]1[CH:11]=[C:10]([CH2:12][C:13]([NH:15][CH:16]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]2[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[CH2:17][CH:18]([CH3:19])[CH3:20])=[O:14])[CH:9]=[CH:8][C:5]=1[CH2:6][C:33]#[N:34])[CH3:2]

Participants

Reactant 2

HCID 8929Sodium Cyanide

HCID 21261834HCID 21261834, compound

Product 1

HCID 21261854HCID 21261854, compound

Procedure

Prepared analogously to Example 1 from 2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]benzyl chloride with sodium cyanide.

Sources & evidence

ORD record: ord-70701a3552044a6a98919cc10fed203e
Source dataset: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05312924

Reaction notes

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