HCID 88427648, compound → HCID 19023596, compound

Participants

Reaction Steps

A solution of oxime of Example N (3.08 g, 10.6 mmol) in EtOH (80 ml) was hydrogenated at 1000 psi at 70° C. on 10% palladium on carbon. Filtration and concentration of the filtrate gave an oil which was chromatographed on silica gel eluting with 2/97.75/0.25 EtOH/CH2Cl2 /NH4OH to afford the title compound (1.76 g, 60%) as a white solid. Anal calcd for C15H20N2O3 : C, 65.20; H, 7.30; N, 10.14. Found: C, 64.95; H, 7.39; N, 10.04. MS Calcd for C15H20N2O3 276, found 276. DSC=105.0°-121.1° at 57.2 J/g.

Provenance & Evidence