Trifluoroacetic acid → HCID 67793165, compound

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Reaction Steps

The tert-butyl ester of example 58 (320 mg, 0.686 mmol) was dissolved trifluoroacetic acid (2 ml) and stirred for 2.5 h after which time the reaction was concentrated in vacuo. The resulting material was recrystallized from CH2Cl2 /CH3OH to give 116 mg (41%) of the title compound as a white solid. Anal. calcd. for C21H18N2O5S.1/4H2O: C,60.79; H,4.49; N,6.75. Found: C,60.94; H,4.45; N,6.71. MS calc for C21H18N2O5S 410, found 410. DSC=221.0°-224.1° C. at 109.2 J/g.

Provenance & Evidence