HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-2-carboxylic acid → cis-4-[(1H-Indol-2-ylcarbonyl)amino]-5-oxo-1-phenyl-3-pyrrolidineacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-2-carboxylic acid | HCID 72899 | — |
| Reactant | Ethyl 4-(hydroxyimino)-5-oxo-1-phenyl-3-pyrrolidineacetate | HCID 86746704 | — |
| Product | cis-4-[(1H-Indol-2-ylcarbonyl)amino]-5-oxo-1-phenyl-3-pyrrolidineacetic acid | HCID 67795074 | — |
Reaction Steps
The aminopyrrolidinone of Example 63 is coupled with indole-2-carboxylic acid according to the procedure described in Example 4 and the resulting ester is saponified to give the title homologated acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05314886 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-a8f0b2a4ea82421c9421b0ac8096fdcf |
| Source note | uspto-grants-1994_05 |