Chlorosulfonic acid → HCID 11858354, compound

HRID 1034539Notes

Reaction equation

HRID 1034539 reaction equation
Cl[S:2]([OH:5])(=[O:4])=[O:3].[C:6]([O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=1)(=[O:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>ClCCl>[C:6]([O:14][C:15]1[CH:20]=[CH:19][C:18]([S:2]([OH:5])(=[O:4])=[O:3])=[C:17]([O:21][CH3:22])[CH:16]=1)(=[O:13])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 24638Chlorosulfonic acidHCID 2828833-Methoxyphenyl benzoate

Product 1

HCID 11858354HCID 11858354, compoundYield 15%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A solution of 0.47 mL (7.01 mmol) of chlorosulfonic acid in 7 mL of dichloromethane was added drop by drop to a solution of 1.6 g (7.01 mmol) of 3-methoxyphenyl benzoate in 12 mL of dichloromethane at 0° C. Once the addition was completed, the mixture was left to react for 18 h at room temperature. The formed precipitate was filtered, giving 300 mg of 4-benzoyloxy-2-methoxybenzenesulfonic acid. Yield 15%.

Workup

  1. additionOnce the addition
  2. waitthe mixture was left
  3. customto react for 18 h at room temperature
  4. filtrationThe formed precipitate was filtered

Sources & evidence

ORD record
ord-09ab99da962f4449a01def9c526a843d
Source dataset
uspto-grants-2013_10
Patent number
US08545816B2

Reaction notes

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