反应详情

830 mg of (S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester (VIII, R1=ethyl) were suspended in 0.8 mL of H2O. 900 mg of 50% aqueous KOH were added. After 5 h at 25° C. conversion was complete (determination by HPLC). The solvent was removed under reduced pressure to give a solid consisting of the title compound and minor amounts of KOH.

1. customThe solvent was removed under reduced pressure
2. customto give a solid