Acetic Acid → HCID 136508367, compound

Participants

Reaction Steps

A solution of Example 72A (2.0 g, 4.5 mmol) in acetic acid (10 ml) was treated with Raney nickel (200 mg) at rt. The reaction mixture was stirred under hydrogen for 6 h. Solid material was filtered off and the filtrate was concentrated. The residue was separated by flash chromatography to give Example 77A. Yield: 0.5 g (25%). MS (DCI): m/z 449 (M+H)+.

Provenance & Evidence