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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1034997Generated: October 27, 2026

1-Methyl-3-pyrrolidinol → 2-((1-Methylpyrrolidin-3-yl)oxy)nicotinonitrile

https://huagongshe.com/reaction/1034997

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-pyrrolidinolHCID 93074—
Reactant3-Cyano-2-fluoropyridineHCID 2783254—
Product2-((1-Methylpyrrolidin-3-yl)oxy)nicotinonitrileHCID 68585106—

Reaction Steps

2-Fluoro-nicotinonitrile was reacted with 1-methyl-pyrrolidin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 204 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546374B2
Source datasetuspto-grants-2013_10
ORD IDord-e8ee7cbe0b014dc3bc03f63b78ac8e5a
Source noteuspto-grants-2013_10