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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035005Generated: October 25, 2026

3-Cyano-2-fluoropyridine → 2-(6-Chloro-5-fluoro-pyridin-3-yloxy)-nicotinonitrile

https://huagongshe.com/reaction/1035005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyano-2-fluoropyridineHCID 2783254—
Reactant2-Chloro-3-fluoro-5-hydroxypyridineHCID 40424737—
Product2-(6-Chloro-5-fluoro-pyridin-3-yloxy)-nicotinonitrileHCID 86082295—

Reaction Steps

2-Fluoro-nicotinonitrile was reacted with 6-chloro-5-fluoro-pyridin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 250 (M)+, 252 (M+2)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546374B2
Source datasetuspto-grants-2013_10
ORD IDord-a4585b0bde3848af985c53a0a86e8db4
Source noteuspto-grants-2013_10