2-(4-Pyridinyl)benzaldehyde → [2-(Pyridin-4-yl)phenyl]methanol

HRID 1035021Notes

Reaction equation

HRID 1035021 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=2[CH:9]=[O:10])=[CH:3][CH:2]=1.[BH4-].[Na+]>>[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=2[CH2:9][OH:10])=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 6428502-(4-Pyridinyl)benzaldehydeHCID 4311764Sodium borohydride

Product 1

HCID 14955123[2-(Pyridin-4-yl)phenyl]methanol

Procedure

2-pyridin-4-yl-benzaldehyde was treated with NaBH4 according to the method of Example 119A to provide the title compound. MS (ESI+) m/z 185 (M+H)+;

Sources & evidence

ORD record
ord-f11c9bdac255462cb329c4ad76591a41
Source dataset
uspto-grants-2013_10
Patent number
US08546374B2

Reaction notes

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