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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035047Generated: November 3, 2026

Hydrochloric Acid → 1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime

https://huagongshe.com/reaction/1035047

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantO-MethylhydroxylamineHCID 4113—
Reactant1'-methylspiro[indene-1,4'-piperidin]-3(2H)-oneHCID 53712826—
Product1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloximeHCID 86082279—

Reaction Steps

The product of Example 138B and the HCl salt of methoxylamine were processed according to the method of Example 135A to provide the product. MS (ESI+) m/z 245 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546374B2
Source datasetuspto-grants-2013_10
ORD IDord-62377a22b32846138b947f7f44e81c02
Source noteuspto-grants-2013_10