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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035048Generated: November 3, 2026

1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime → 1'-Methyl-2,3-dihydrospiro[indene-1,4'-piperidin]-3-amine

https://huagongshe.com/reaction/1035048

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloximeHCID 86082279—
CatalystNickelHCID 935—
Product1'-Methyl-2,3-dihydrospiro[indene-1,4'-piperidin]-3-amineHCID 68584498—

Reaction Steps

The product of Example 138C and Raney/nickel were processed according to the method of Example 131C to provide the product. MS (ESI+) m/z 217 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546374B2
Source datasetuspto-grants-2013_10
ORD IDord-7af828ed9e394339b86269f5221fe3ec
Source noteuspto-grants-2013_10