HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloronicotinonitrile → 2-(2-Chlorophenyl)-3-pyridinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloronicotinonitrile | HCID 81079 | — |
| Reactant | 2-Chlorophenylboronic acid | HCID 2734322 | — |
| Product | 2-(2-Chlorophenyl)-3-pyridinecarbonitrile | HCID 53904302 | 18% |
Reaction Steps
Prepared in 18% yield from 2-chloro-3-cyanopyridine and 2-chlorophenylboronic acid according to the procedure described for Example 153A. MS (ESI−) m/z 215.0 (M+H)+; 1H NMR (CDCl3) δ 7.41-7.49 (m, 4H), 7.53-7.56 (m, 1H), 8.09 (dd, J=7.8, 1.7 Hz, 1H), 8.90 (dd, J=5.1, 1.7 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546374B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-d377731c81a24f479b007a36eb53c49f |
| Source note | uspto-grants-2013_10 |