HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloronicotinonitrile → HCID 68584169, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloronicotinonitrile | HCID 81079 | — |
| Reactant | (2,3-Difluorophenyl)boronic acid | HCID 2734333 | — |
| Product | HCID 68584169 | HCID 68584169 | 91% |
Reaction Steps
Prepared in 91% yield from 2-chloronicotinonitrile and 2,3-difluorophenylboronic acid according to the procedure described for Example 153A. MS (ESI−) m/z 216.9 (M+H)+; 1H NMR (CDCl3) δ 7.21-7.29 (m, 1H), 7.30-7.39 (m, 2H), 7.49 (dd, J=8.0, 4.9 Hz, 1H), 8.12 (dd, J=7.8, 1.7 Hz, 1H), 8.92 (dd, J=4.9, 1.9 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546374B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-7da66d8dddec4aed8d174ce6085cc967 |
| Source note | uspto-grants-2013_10 |