HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylate → HCID 58043089, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylate | HCID 13407471 | — |
| Reactant | 1-(5-Phenyl-1,3,4-oxadiazole-2-carbonyl)azetidin-3-yl methanesulfonate | HCID 58043099 | — |
| Reactant | HCID 58043105 | HCID 58043105 | — |
| Product | HCID 58043089 | HCID 58043089 | 32% |
Reaction Steps
Using similar protocols as described in Example 53A, 53B and 53C employing ethyl 5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylate as starting material afforded 0.47 g (32%) of 55A as a solid. 1H NMR (500 MHz, CDCl3): δ 3.89 (s, 3H), 4.36 (d, 1H), 4.70 (dd, 1H), 4.79 (m, 1H), 5.18 (m, 2H), 6.91 (d, 2H), 7.03 (d, 2H), 7.88 (d, 2H), 8.10 (d, 2H), 9.93 (s, 1H), MS (APCI+) m/z 380 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546375B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-df25f0b5774248ada475bbad87cefee2 |
| Source note | uspto-grants-2013_10 |