HRID1035244

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID458185

4-Hydroxy-2-methylbenzaldehyde

C8H8O2

结构：COc1ccc(-c2nnc(C(=O)N3CC(OS(C)(=O)=O)C3)o2)cc1

HCID58043131

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(C=O)c(C)c4)C3)o2)cc1

HCID58043156

Benzaldehyde, 4-[[1-[[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]carbonyl]-3-azetidinyl]oxy]-2-methyl-

C21H19N3O5

收率 67%

PROCEDURE

实验过程

Using a similar protocol as described in Example 71A employing 73B and 4-hydroxy-2-methylbenzaldehyde as starting materials afforded 9.4 g (67%) of 73C as a solid. 1H NMR (500 MHz, CDCl3): δ 2.67 (s, 3H), 3.89 (s, 3H), 4.37 (m, 1H), 4.70 (m, 1H), 4.78 (m, 1H), 5.15 (m, 2H), 6.65 (s, 1H), 6.74 (d, 1H), 7.02 (d, 2H), 7.78 (d, 1H), 8.11 (d, 2H), 10.2 (s, 1H).