HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-tert-Butyl-5-isocyanato-1-p-tolyl-1H-pyrazole → 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-tert-Butyl-5-isocyanato-1-p-tolyl-1H-pyrazole | HCID 17987855 | — |
| Reactant | Tert-butyl 4-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenylcarbamate | HCID 46900574 | — |
| Product | 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea | HCID 44133906 | 55% |
Reaction Steps
Method E1 was used with Tert-butyl 4-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenylcarbamate and 3-tert-butyl-5-isocyanato-1-p-tolyl-1H-pyrazole to obtain the title compound (yield 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546387B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-6c0799e80d5b486f87b2702cdd3ed00d |
| Source note | uspto-grants-2013_10 |