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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035411Generated: November 4, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → HCID 44134088, compound

https://huagongshe.com/reaction/1035411

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
ReactantHCID 59588864HCID 59588864—
ProductHCID 44134088HCID 44134088—

Reaction Steps

Method F2 was used with 8-(4-aminophenylthio)pyrido[2,3-b]pyrazin-3(4H)-one (36.7 mg, 136 μmol) and 2-fluoro-5-trifluoromethyl-phenylisocyanate (22.5 μL, 156 136 μmol) to afford the title compound. Yield: 53 mg (82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546387B2
Source datasetuspto-grants-2013_10
ORD IDord-b397c4d7f1854e92904b8068572ad5cd
Source noteuspto-grants-2013_10