HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59443486, compound → HCID 59443475, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59443486 | HCID 59443486 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 59443475 | HCID 59443475 | — |
Reaction Steps
A suspension of (E)-3-[3-methoxy-5-(6-methoxynaphthalene-2-yl)phenyl]acrylic acid (100 mg, 0.30 mmol, 1 eq) and Pd(OH)2 (2.82 mg) in ethanol (1 ml) and THF (0.4 ml) is stirred at RT under a hydrogen atmosphere for 23 h. The reaction mixture is filtered and concentrated in vacuum on a rotary evaporator to obtain the compound in quantitative yield (100 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-ef1a101eef514a1da6f87437440d659c |
| Source note | uspto-grants-2013_10 |