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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035592Generated: October 30, 2026

HCID 59443486, compound → HCID 59443475, compound

https://huagongshe.com/reaction/1035592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59443486HCID 59443486—
CatalystPalladium hydroxideHCID 9942167—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 59443475HCID 59443475—

Reaction Steps

A suspension of (E)-3-[3-methoxy-5-(6-methoxynaphthalene-2-yl)phenyl]acrylic acid (100 mg, 0.30 mmol, 1 eq) and Pd(OH)2 (2.82 mg) in ethanol (1 ml) and THF (0.4 ml) is stirred at RT under a hydrogen atmosphere for 23 h. The reaction mixture is filtered and concentrated in vacuum on a rotary evaporator to obtain the compound in quantitative yield (100 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546392B2
Source datasetuspto-grants-2013_10
ORD IDord-ef1a101eef514a1da6f87437440d659c
Source noteuspto-grants-2013_10