2-Bromo-6-methoxynaphthalene → 2-Methoxy-6-(3-methoxyphenyl)naphthalene

Participants

Reaction Steps

The compound is prepared by the reaction of 2-bromo-6-methoxynaphthalene (500 mg, 2.11 mmol, 1 eq) with 3-methoxyphenylboric acid (321 mg, 2.11 mmol, 1 eq) according to method A within 22 h. Purification by column chromatography with a mixture of hexane/ethyl acetate 9/1 yields the desired product in a yield of 81% (451 mg).

Provenance & Evidence