HCID 68482452, compound → HCID 59443451, compound

HRID 1035619Notes

Reaction equation

HRID 1035619 reaction equation
Br[C:2]1[CH:3]=[C:4]([S:8]([NH:11][C:12]2[S:13][C:14]([CH3:17])=[N:15][N:16]=2)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[CH3:18][O:19][C:20]1[CH:29]=[CH:28][C:27]2[C:22](=[CH:23][CH:24]=[C:25]([C:30]3[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[CH:31]=3)[CH:26]=2)[C:21]=1OB(O)O>CCOCC>[CH3:18][O:19][C:20]1[CH:29]=[CH:28][C:27]2[C:22](=[CH:23][CH:24]=[C:25]([C:30]3[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[CH:31]=3)[CH:26]=2)[C:21]=1[C:2]1[CH:3]=[C:4]([S:8]([NH:11][C:12]2[S:13][C:14]([CH3:17])=[N:15][N:16]=2)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 68482452HCID 68482452, compoundHCID 68484099HCID 68484099, compound

Product 1

HCID 59443451HCID 59443451, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The compound is prepared by the reaction of 3-bromo-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide (92.4 mg, 0.28 mmol, 1 eq) with 2-methoxy-6-(3-methoxyphenyl)naphthalene-1-ylboric acid (100 mg, 0.36 mmol, 1.3 eq) according to method C. The raw product was not characterized, but directly subjected to ether cleavage.

Sources & evidence

ORD record
ord-31d35bc05cec43c0b5c1ecabf8580793
Source dataset
uspto-grants-2013_10
Patent number
US08546392B2

Reaction notes

Loading…