Methylamine → HCID 59443466, compound

Participants

Reaction Steps

The compound was prepared by reaction of (E)-3-[3-methoxy-5-(6-methoxynaphthalene-2-yl)phenyl]acrylic acid (300 mg, 0.89 mmol, 1 eq) with 33% methylamine (1 eq) according to method D. Purification by column chromatography with hexane/ethyl acetate 2/1 as the eluent yielded the desired product in a yield of 53%, 200 mg.

Provenance & Evidence