HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 2-(3-Hydroxyphenyl)quinolin-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 6-Methoxy-2-(3-methoxyphenyl)quinoline | HCID 22064610 | — |
| Product | 2-(3-Hydroxyphenyl)quinolin-6-ol | HCID 25069444 | 10% |
Reaction Steps
The compound is prepared by reaction of 6-methoxy-2-(3-methoxyphenyl)quinoline (77 mg, 0.29 mmol, 1 eq) with boron tribromide (15 eq) according to method G. Purification by column chromatography with hexane/ethyl acetate 7/3 as the eluent yields the desired product in a yield of 10%, 7 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-dcdb294dd069481abc4d45da19ed107c |
| Source note | uspto-grants-2013_10 |