HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Methoxyphenyl)quinoline → 3-Quinolin-3-ylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Methoxyphenyl)quinoline | HCID 4134298 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | 3-Quinolin-3-ylphenol | HCID 20099949 | 85% |
Reaction Steps
The compound is prepared by reaction of 3-(3-methoxyphenyl)quinoline (101 mg, 0.43 mmol, 1 eq) with aluminum trichloride (341 mg, 2.57 mmol, 6 eq) according to method F. Purification by preparative thin-layer chromatography with dichloromethane/methanol 95/5 (DC plates coated with 1 mm thick coating) yields the desired product in a yield of 85%, 81 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-2d9a0552ec6b40b89cf6b190f359b5dc |
| Source note | uspto-grants-2013_10 |