HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methoxyphenyl)quinoline → 4-Quinolin-3-ylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methoxyphenyl)quinoline | HCID 4134297 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | 4-Quinolin-3-ylphenol | HCID 11746183 | 82% |
Reaction Steps
The compound is prepared by reaction of 3-(4-methoxyphenyl)quinoline with aluminum trichloride (564 mg, 4.23 mmol, 5 eq) according to method F. Purification by column chromatography with dichloromethane/methanol 99/1 as the eluent yields the desired product in a yield of 82%, 156 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-34947dd94fd84b3995f4677b80d8b771 |
| Source note | uspto-grants-2013_10 |