HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 6-(3-Hydroxyphenyl)-2-naphthol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 2-Methoxy-6-(3-methoxyphenyl)naphthalene | HCID 11402834 | — |
| Product | 6-(3-Hydroxyphenyl)-2-naphthol | HCID 10192730 | 52% |
Reaction Steps
The compound is prepared by reaction of 2-methoxy-6-(3-methoxyphenyl)-naphthalene (51 mg, 0.19 mmol, 1 eq) with boron tribromide (0.6 ml, 0.60 mmol, 3 eq) according to method G. Purification by column chromatography with dichloromethane/methanol 98/2 as the eluent yields the desired product in a yield of 52%, 23 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-387a5f68d7f244eb9f173235f0aeffc9 |
| Source note | uspto-grants-2013_10 |