Boron tribromide → HCID 24950550, compound

HRID 1035663Notes

Reaction equation

C[O:2][C:3]1[C:4]([C:21]([NH:23][CH3:24])=[O:22])=[CH:5][C:6]2[C:11]([CH:12]=1)=[CH:10][CH:9]=[C:8]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19]C)[CH:14]=1)[CH:7]=2.B(Br)(Br)Br>>[OH:2][C:3]1[C:4]([C:21]([NH:23][CH3:24])=[O:22])=[CH:5][C:6]2[C:11]([CH:12]=1)=[CH:10][CH:9]=[C:8]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([OH:19])[CH:14]=1)[CH:7]=2

Participants

Reactant 2

HCID 25134Boron tribromide

HCID 59443458HCID 59443458, compound

Product 1

HCID 24950550HCID 24950550, compound

Procedure

The compound is prepared by reaction of 3-methoxy-7-(3-methoxyphenyl)-N-methyl-2-naphthamide (93 mg, 0.29 mol, 1 eq) with boron tribromide solution (5.5 ml, 5.5 mmol, 19 eq) according to method G. Purification was not necessary. The desired product was obtained in quantitative yield.

Workup

customPurification

Sources & evidence

ORD record: ord-376f9858a6464249a6247c290aa12ae8
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08546392B2

Reaction notes

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