Boron tribromide → HCID 24950391, compound

HRID 1035670Notes

Reaction equation

HRID 1035670 reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([O:18]C)[CH:13]=3)=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:20]C.B(Br)(Br)Br>>[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([OH:18])[CH:13]=3)=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[OH:20]

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 59443446HCID 59443446, compound

Product 1

HCID 24950391HCID 24950391, compound

Procedure

The compound is prepared by reaction of 1-bromo-2-methoxy-6-(3-methoxyphenyl)naphthalene (500 mg, 1.46 mmol, 1 eq) with boron tribromide solution (7.3 ml, 7.3 mmol, 5 eq) according to method G. Purification of the raw product was not necessary. The desired product was obtained in quantitative yield (460 mg).

Workup

  1. customPurification of the raw product

Sources & evidence

ORD record
ord-951fcf99e8134335ba30efdcd7b412e8
Source dataset
uspto-grants-2013_10
Patent number
US08546392B2

Reaction notes

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