HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 5-Chloro-3-(2-ethoxyphenyl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | Benzene, 1-ethoxy-2-iodo- | HCID 136415 | — |
| Reactant | 5-Chloro-6-fluoroindoline-2,3-dione | HCID 16781873 | — |
| Product | 5-Chloro-3-(2-ethoxyphenyl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-one | HCID 67087463 | — |
Reaction Steps
The title compound was prepared in analogy to example a.1 using 5-chloro-6-fluoro-isatin as isatin II and ethoxyiodobenzene (to form the Grignard reagent).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546401B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-914871c572a34eec8f78afc2914bf16d |
| Source note | uspto-grants-2013_10 |