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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1035926Generated: October 31, 2026

tert-Butyl piperazine-1-carboxylate → HCID 86648178, compound

https://huagongshe.com/reaction/1035926

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant4'-Chlorobiphenyl-2-carbaldehydeHCID 1393689—
Reactant(3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidineHCID 1514396—
ProductHCID 86648178HCID 86648178—

Reaction Steps

The title compound was prepared by substituting 2,2-dimethyldihydro-2H-pyran-4(3H)-one for 4′-chlorobiphenyl-2-carboxaldehyde and (S)-tert-butyl pyrrolidin-3-ylcarbamate for tert-butyl piperazine-1-carboxylate in EXAMPLE 1A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546399B2
Source datasetuspto-grants-2013_10
ORD IDord-21fb6e00e515469a95692c06f546d660
Source noteuspto-grants-2013_10