Acetyl chloride → HCID 86648179, compound

HRID 1035940Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5]C[CH:3]([CH2:7][NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])[CH2:2]1.[C:16](Cl)(=[O:18])[CH3:17].CS(Cl)(=O)=O>>[C:16]([N:1]1[CH2:6][CH2:5][CH:3]([CH2:7][NH:8][C:9](=[O:15])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:2]1)(=[O:18])[CH3:17]

Participants

Reactant 3

HCID 6367Acetyl chloride

HCID 31297Methanesulfonyl chloride

HCID 2756030tert-butyl N-[(piperidin-3-yl)methyl]carbamate

Product 1

HCID 86648179HCID 86648179, compound

Procedure

The title compound was prepared by substituting tert-butyl pyrrolidin-3-ylmethylcarbamate for tert-butyl piperidin-3-ylmethylcarbamate and acetyl chloride for methanesulfonyl chloride in EXAMPLE 147A.

Sources & evidence

ORD record: ord-9217b9e608064f7e8e642660dbca2a4d
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08546399B2

Reaction notes

Loading…