HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → (R)-tert-butyl 1-(oxetan-3-yl)pyrrolidin-3-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 4'-Chlorobiphenyl-2-carbaldehyde | HCID 1393689 | — |
| Reactant | 3-Oxetanone | HCID 15024254 | — |
| Product | (R)-tert-butyl 1-(oxetan-3-yl)pyrrolidin-3-ylcarbamate | HCID 56604507 | — |
Reaction Steps
The title compound was prepared by substituting (R)-tert-butyl pyrrolidin-3-ylcarbamate for tert-butyl piperazine-1-carboxylate and 3-oxetanone for 4′-chlorobiphenyl-2-carboxaldehyde in EXAMPLE 1A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546399B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-befcfdca29a743dda838e7b108494811 |
| Source note | uspto-grants-2013_10 |