(3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidine → HCID 44513881, compound

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Reaction Steps

The compound from Example 8C (65 mg, 0.168 mmol) was treated with (R)-tert-butyl pyrrolidin-3-ylcarbamate (36 mg, 0.2 mmol) as described in Example 2 to yield the title compound: 1H NMR (300 MHz, DMSO-d6) δ 7.80 (s, 1 H), 5.5 (br s, 2 H), 3.73 (m, 3 H), 3.55 (m, 2 H), 3.42 (m, 2 H), 3.11 (m, 1 H), 2.89 (m, 2 H), 2.59 (m, 2 H), 1.95 (m, 3 H), 1.57 (m, 1 H); MS (ESI+) m/z 300 (M+H)+.

Provenance & Evidence