Trifluoroacetic acid → HCID 68528683, compound

Participants

Reaction Steps

The product from Example 11E (5 mg) was dissolved in dichloromethane (0.5 ml) and treated with trifluoroacetic acid (0.5 mL) for 1 hour at ambient temperature. The reaction mixture was concentrated and triturated with ether to yield the title compound: 1H NMR (300 MHz, DMSO-d6) δ 8.66 (s, 1 H), 8.16 (s, 1 H), 7.59 (m, 5 H), 3.84 (m, 2 H), 2.91 (t, J=6.78 Hz, 2 H), 2.67 (m, 4H), 2.45 (s, 3H), 2.27 (m, 2 H), 2.14 (m, 3 H); MS (ESI+) m/z 376 (M+H)+.

Provenance & Evidence