HRID1036417

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)NC1(c2ccc3cc(O)ccc3c2)COC(C)(C)OC1

HCID44228963

tert-Butyl [5-(6-hydroxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxan-5-yl]carbamate

C21H27NO5

HCID178445811

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NC1(c2ccc3cc(O[C@H]4CC[C@H](C(C)(C)C)CC4)ccc3c2)COC(C)(C)OC1

HCID178452577

未命名化合物

收率 42%

PROCEDURE

实验过程

The title compound was prepared from cis-4-tertbutylcyclohexanol and [5-[6-hydroxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxinan-5-yl]-carbamic acid tert-butyl ester in 42% yield according to the method of Example 53.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1a2061bcc3b942dd9a7eacffab1b2b8d
来源数据集: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08546359B2
来源说明: uspto-grants-2013_10

反应 SMILES

[C:1]([C@@H:5]1[CH2:10][CH2:9][C@H:8]([OH:11])[CH2:7][CH2:6]1)([CH3:4])([CH3:3])[CH3:2].[C:12]([O:16][C:17](=[O:38])[NH:18][C:19]1([C:27]2[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[C:32](O)[CH:33]=3)[CH:28]=2)[CH2:24][O:23][C:22]([CH3:26])([CH3:25])[O:21][CH2:20]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:38])[NH:18][C:19]1([C:27]2[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[C:32]([O:11][C@H:8]4[CH2:7][CH2:6][C@H:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[CH2:10][CH2:9]4)[CH:33]=3)[CH:28]=2)[CH2:20][O:21][C:22]([CH3:26])([CH3:25])[O:23][CH2:24]1)([CH3:13])([CH3:14])[CH3:15]