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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1036498Generated: October 30, 2026

(R)-4-(5-chloro-6-hydroxynaphthalen-2-yl)-4-methyloxazolidin-2-one → HCID 178445735, compound

https://huagongshe.com/reaction/1036498

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-4-(5-chloro-6-hydroxynaphthalen-2-yl)-4-methyloxazolidin-2-oneHCID 67415649—
ReactantHCID 178445722HCID 178445722—
ProductHCID 178445735HCID 17844573557%

Reaction Steps

(R)-4-(6-(trans-4-tert-butylcyclohexyloxy)-5-chloronaphthalen-2-yl)-4-methyloxazolidin-2-one was synthesized as per (R)-4-(5-bromo-6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)-4-methyloxazolidin-2-one (Example 213) in 57% yield using (R)-4-(5-chloro-6-hydroxynaphthalen-2-yl)-4-methyloxazolidin-2-one as the to starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546359B2
Source datasetuspto-grants-2013_10
ORD IDord-1728fe6008c6433b88571ee3703b94ae
Source noteuspto-grants-2013_10