Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | N-Phthaloyl-DL-glutamic anhydride | HCID 92193 | — |
| Product | N-phenethyl phthalimide | HCID 348641 | — |
Reaction Steps
With reference to Scheme 3 below, a mixture of N-phthaloyl-DL-glutamic anhydride and phenethylamine was heated in a 177° C. oil bath. The reaction mixture was purified by chromatography on a silica gel column to afford N-phenethylthalidomide (8) and N-phenethylphthalimide (9).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08546430B2 |
|---|
| Source dataset | uspto-grants-2013_10 |
|---|
| ORD ID | ord-1bc4e086e8f848faa9f0133818553737 |
|---|
| Source note | uspto-grants-2013_10 |
|---|
