反应详情

The title compound was prepared from 4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid and 6-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-ol by the same method as described for 4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-methylbenzamide. It was obtained as a white solid. 1H NMR (400 MHz, DMSO-d6): δ 9.21 (s, 1 H), 8.94 (m, 1 H), 7.37-7.82 (m, 9 H), 4.95 (s, 2 H), 4.49 (m, 2 H), 4.34 (m, 2 H), 2.37 (s, 3 H) ppm; MS: m/z=563 (M+1, ESI+).

1. customIt was obtained as a white solid