(NE)-N-[1-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)ethylidene]hydroxylamine → 6-(1-aminoethyl)-3,3-dimethylbenzo[c][1,2]oxaborol-1(3H)-ol

Participants

Reaction Conditions

Reaction Steps

A mixture of crude compound (E)-1-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)ethanone oxime (0.93 mmol) and zinc dust (260 mg, 4.0 mmol) in AcOH (8 mL) was heated to 40° C. and stirred for 0.5 h. LC-MS showed SM disappeared. The reaction mixture was used for next reaction directly without being purified.

Provenance & Evidence