HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-ol → 8-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)indolizine-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-ol | HCID 68281533 | — |
| Reactant | 8-[5-(Trifluoromethyl)-5-(3,5-dichlorophenyl)-2-isoxazoline-3-yl]indolizine-5-carboxylic acid | HCID 86685522 | — |
| Product | 8-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)indolizine-5-carboxamide | HCID 71576578 | — |
Reaction Steps
The title compound can be prepared from 8-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)indolizine-5-carboxylic acid and 6-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-ol as shown by the following scheme:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546357B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-f6ff28ac6d174641ba7b94400c6c7d40 |
| Source note | uspto-grants-2013_10 |